

| Каталожный номер | HV137021 |
|---|---|
| Описание |
Recombinant Human CD85h/LILRA2 Protein, C-Fc (HV137021) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | Mammalian cells |
| Номер доступа | Q8N149 |
| Длина белка | Met1-Asn449(Ser135Leu) |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 75.75 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | CD85 antigen-like family member H, CD85h, ILT-1, ILT1, Immunoglobulin-like transcript 1, LILRA2, LIR-7, LIR7, Leukocyte immunoglobulin-like receptor 7, Leukocyte immunoglobulin-like receptor subfamily A member 2 |
| Фон | Leukocyte immunoglobulin-like receptor subfamily A member 2 is a ~52 kDa protein. Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils. 1. Tedla, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1174-9. PMID: 12529506 2. Hirayasu, K. et al. (2016) Nature microbiology 1, 16054. PMID: 27572839 3. Lu, HK. et al. (2012) PloS one 7, e33478. PMID: 22479404 4. Chen, Y. et al. (2009) Journal of molecular biology 386, 841-53. PMID: 19230061 |
| Примечание | For research use only |



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