Recombinant Human CD91/LRP1 Protein, C-Fc (HC475011) expressed in Mammalian Cells, spanning Arg786-Leu1165. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии
Mammalian cells
Номер доступа
Q07954
Длина белка
Arg786-Leu1165
Применения
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды
Homo sapiens (Human)
Характер
Recombinant
Уровень эндотоксинов
Please contact with the lab for this information.
Чистота
>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса
69.85 kDa
Форма
Lyophilized
Буфер хранения
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия
A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, CD91, LRP-1, LRP-515, LRP-85, LRP1, LRPICD, Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Prolow-density lipoprotein receptor-related protein 1
Фон
Prolow-density lipoprotein receptor-related protein 1 is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor.
1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044
2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657
3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392
4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438
中文
English
한국어
日本語
Español
Français
Русский
