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| カタログ番号 | HF842022 |
|---|---|
| 説明 |
Recombinant Human CDS2 Protein, N-GST & C-His (HF842022) expressed in E. coli, spanning Ser282-Ser339. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O95674 |
| タンパク質長 | Ser282-Ser339 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 34.95 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CDP-DAG synthase 2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-diglyceride pyrophosphorylase 2, CDP-diglyceride synthase 2, CDS 2, CDS2, CTP:phosphatidate cytidylyltransferase 2, EC:2.7.7.41, Phosphatidate cytidylyltransferase 2 |
| 背景 | Phosphatidate cytidylyltransferase 2 is a ~51 kDa protein. Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. 1. D'Souza, K. et al. (2014) Biochemistry 53, 7358-67. PMID: 25375833 2. Qi, Y. et al. (2016) Journal of lipid research 57, 767-80. PMID: 26946540 3. Xu, Y. et al. (2019) The Journal of biological chemistry 294, 16740-16755. PMID: 31548309 |
| 注意事項 | For research use only |
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