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Anti-Human CDS2 Polyclonal Antibody (HF842014)

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Overview
Catalog No.HF842014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CDS2 (Ser282-Ser339).
Target Phosphatidate cytidylyltransferase 2, CDP-diglyceride pyrophosphorylase 2, CDS2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-DAG synthase 2, CDP-diglyceride synthase 2, CDS 2, CTP:phosphatidate cytidylyltransferase 2
Purification Purified by antigen affinity column.
Accession O95674
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Phosphatidate cytidylyltransferase 2 (CDS2) is a ~51 kDa protein. Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis.

1. D'Souza, K. et al. (2014) Biochemistry 53, 7358-67. PMID: 25375833
2. Qi, Y. et al. (2016) Journal of lipid research 57, 767-80. PMID: 26946540
3. Xu, Y. et al. (2019) The Journal of biological chemistry 294, 16740-16755. PMID: 31548309
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human CDS2 Polyclonal Antibody

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