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| カタログ番号 | HC339021 |
|---|---|
| 説明 |
Recombinant Human CDw210b/IL10RB Protein, C-His (HC339021) expressed in Mammalian Cells, spanning Met1-Ser220. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Mammalian cells |
| アクセッション番号 | Q08334 |
| タンパク質長 | Met1-Ser220 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 26.38 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CDw210b, CRF2-4, CRFB4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, D21S58, D21S66, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, IL10RB, Interleukin-10 receptor subunit 2, Interleukin-10 receptor subunit beta |
| 背景 | Interleukin-10 receptor subunit beta is a ~36 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. |
| 注意事項 | For research use only |
Detected by SAA2106 (Catalog No: HC339017) in indirect ELISA.
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