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Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106) (HC339017)

Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)
Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)
Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)
Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)
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Overview
Catalog No.HC339017
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeVHH-mFc (IgG2a)
Clone IDSAA2106
Clonality Monoclonal
Target Interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2, CDw210b, IL10RB, CRFB4, D21S58, D21S66
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q08334
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Interleukin-10 receptor subunit beta (CDw210b/IL10RB) is a ~36 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Note For research use only.
Images
  • Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)

    SDS-PAGE

    SDS-PAGE for Anti-Human CDw210b/IL10RB Antibody (SAA2106)

  • Anti-Human CDw210b/IL10RB Recombinant Antibody (SAA2106)

    Bioactivity

    Detects recombinant IL10RB (Catalog No: HC339021) in indirect ELISA.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₂ (Working Conc.)
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