

| Numéro de catalogue | HP186022 |
|---|---|
| Description |
Recombinant Human CENPJ Protein, N-His (HP186022) expressed in E. coli, spanning Ile1149-Leu1338. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q9HC77 |
| Longueur de protéine | Ile1149-Leu1338 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 23.99 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CENP-J, CENPJ, CPAP, Centromere protein J, Centrosomal P4.1-associated protein, Centrosome assembly and centriole elongation protein, LAG-3-associated protein, LAP, LIP1, LYST-interacting protein 1 |
| Contexte | Centrosomal P4.1-associated protein is a ~153 kDa protein. Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as a microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. 1. Kleylein-Sohn, J. et al. (2007) Developmental cell 13, 190-202. PMID: 17681131 2. Chang, J. et al. (2010) The EMBO journal 29, 2395-406. PMID: 20531387 3. Hung, LY. et al. (2004) Molecular biology of the cell 15, 2697-706. PMID: 15047868 4. Sharma, A. et al. (2016) Developmental cell 37, 362-376. PMID: 27219064 5. Zheng, X. et al. (2016) Nature communications 7, 11874. PMID: 27306797 6. Tang, CJ. et al. (2011) The EMBO journal 30, 4790-804. PMID: 22020124 7. Chang, CW. et al. (2016) Journal of cell science 129, 2501-13. PMID: 27185865 |
| Note | For research use only |
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