Human DEPTOR Recombinant Protein (N-GST & C-His) (HP016022)

Name: Human DEPTOR Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP016022
Price: 211 USD
Availability: InStock

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1mg

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Обзор

Каталожный номер	HP016022
Описание	Recombinant Human DEPTOR Protein, N-GST & C-His (HP016022) expressed in E. coli, spanning Ser316-Cys409. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q8TB45
Длина белка	Ser316-Cys409
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	38.20 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPDC6, DEPTOR, hDEPTOR
Фон	DEP domain-containing mTOR-interacting protein is a ~46 kDa protein. Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity. 1. Peterson, TR. et al. (2009) Cell 137, 873-86. PMID: 19446321 2. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875 3. Zhao, Y. et al. (2011) Molecular cell 44, 304-16. PMID: 22017876 4. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877 5. Yoon, MS. et al. (2015) Molecular cell 58, 549-56. PMID: 25936805 6. Zhao, L. et al. (2018) The Journal of biological chemistry 293, 4883-4892. PMID: 29382726 7. Wälchli, M. et al. (2021) eLife 10. PMID: 34519268 8. Heimhalt, M. et al. (2021) eLife 10. PMID: 34519269
Примечание	For research use only

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Human DEPTOR Recombinant Protein (N-GST & C-His).pdf

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Formula

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C₁ × V₁ = C₂ × V₂

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Working Solution

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