

| Numéro de catalogue | HV696032 |
|---|---|
| Description |
Recombinant Human DGKD Protein, N-His (HV696032) expressed in E. coli, spanning Ser56-Asn314. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q86XP1 |
| Longueur de protéine | Ser56-Asn314 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 31.62 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | DAG kinase eta, DGK-eta, DGKH, Diacylglycerol kinase eta, Diglyceride kinase eta, EC:2.7.1.107 |
| Contexte | Diacylglycerol kinase eta is a ~134 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization. 1. Murakami, T. et al. (2003) The Journal of biological chemistry 278, 34364-72. PMID: 12810723 2. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 3. Yasuda, S. et al. (2009) The Journal of biological chemistry 284, 29559-70. PMID: 19710016 |
| Note | For research use only |
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