

| Número de catálogo | HC693032 |
|---|---|
| Descripción |
Recombinant Human DGKZ Protein, N-His (HC693032) expressed in E. coli, spanning Gly411-Lys624. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q13574 |
| Longitud de proteína | Gly411-Lys624 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 26.33 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | DAG kinase zeta, DAGK6, DGK-zeta, DGKZ, Diacylglycerol kinase zeta, Diglyceride kinase zeta, EC:2.7.1.107, EC:2.7.1.93 |
| Fondo | Diacylglycerol kinase zeta is a ~103 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Does not exhibit an acyl chain-dependent substrate specificity among diacylglycerol species. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro but less efficiently and with a preference for alkylacylglycerols containing an arachidonoyl group. 1. Epand, RM. et al. (2004) Biochemistry 43, 14778-83. PMID: 15544348 2. Epand, RM. et al. (2007) Biochemistry 46, 14225-31. PMID: 18004883 3. Lung, M. et al. (2009) The Journal of biological chemistry 284, 31062-73. PMID: 19744926 4. Shulga, YV. et al. (2011) FEBS letters 585, 4025-8. PMID: 22108654 5. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129 6. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 7. Ding, L. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5519-24. PMID: 9159104 |
| Nota | For research use only |




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