Human FBXL3 Recombinant Protein (N-His) (HD398012)

Name: Human FBXL3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD398012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD398012
Descripción	Recombinant Human FBXL3 Protein, N-His (HD398012) expressed in E. coli, spanning Gly37-Trp428. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9UKT7
Longitud de proteína	Gly37-Trp428
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	46.89 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	F-box and leucine-rich repeat protein 3A, F-box/LRR-repeat protein 3, F-box/LRR-repeat protein 3A, FBL3A, FBXL3, FBXL3A
Fondo	F-box/LRR-repeat protein 3 is a ~48 kDa protein. Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex. 1. Busino, L. et al. (2007) Science (New York, N.Y.) 316, 900-4. PMID: 17463251 2. Yoo, SH. et al. (2013) Cell 152, 1091-105. PMID: 23452855 3. Scott, DC. et al. (2016) Cell 166, 1198-1214.e24. PMID: 27565346
Nota	For research use only

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Datasheet

Human FBXL3 Recombinant Protein (N-His).pdf

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