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| カタログ番号 | HY398032 |
|---|---|
| 説明 |
Recombinant Human FGF2/bFGF Protein, N-His-SUMO (HY398032) expressed in E. coli, spanning Pro143-Ser288. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P09038 |
| タンパク質長 | Pro143-Ser288 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 28.65 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Basic fibroblast growth factor, FGF-2, FGF2, FGFB, Fibroblast growth factor 2, HBGF-2, Heparin-binding growth factor 2, bFGF |
| 背景 | Fibroblast growth factor 2 is a ~30 kDa protein. Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. 1. Ornitz, DM. et al. (1996) The Journal of biological chemistry 271, 15292-7. PMID: 8663044 2. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677 3. Shimoyama, Y. et al. (1991) Japanese journal of cancer research : Gann 82, 1263-70. PMID: 1721615 4. Gautschi, P. et al. (1986) FEBS letters 204, 203-7. PMID: 3732516 5. Gimenez-Gallego, G. et al. (1986) Biochemical and biophysical research communications 135, 541-8. PMID: 3964259 6. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107 |
| 注意事項 | For research use only |
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