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Обзор
Каталожный номерHC631022
Описание
Recombinant Human FOXC1 Protein, N-GST & C-His (HC631022) expressed in E. coli, spanning Tyr81-Glu193. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессииE. coli
Номер доступаQ12948
Длина белкаTyr81-Glu193
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыHomo sapiens (Human)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса 41.81 kDa
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияFKHL7, FOXC1, FREAC-3, FREAC3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3
Фон

Forkhead box protein C1 is a ~56 kDa protein. DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Acts as a transcriptional coactivator.

1. Berry, FB. et al. (2002) The Journal of biological chemistry 277, 10292-7. PMID: 11782474
2. Saleem, RA. et al. (2003) Human molecular genetics 12, 2993-3005. PMID: 14506133
3. Saleem, RA. et al. (2003) Investigative ophthalmology & visual science 44, 4608-12. PMID: 14578375
4. Murphy, TC. et al. (2004) Investigative ophthalmology & visual science 45, 2531-8. PMID: 15277473
5. Saleem, RA. et al. (2004) Nucleic acids research 32, 4182-93. PMID: 15299087
6. Berry, FB. et al. (2005) Molecular and cellular biology 25, 1415-24. PMID: 15684392
7. Berry, FB. et al. (2006) Human molecular genetics 15, 905-19. PMID: 16449236
8. Berry, FB. et al. (2006) The Journal of biological chemistry 281, 10098-104. PMID: 16492674
9. Ito, YA. et al. (2007) Archives of ophthalmology (Chicago, Ill. : 1960) 125, 128-35. PMID: 17210863
10. Ito, YA. et al. (2009) Investigative ophthalmology & visual science 50, 3573-9. PMID: 19279310
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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