Anti-Human FOXC1 Polyclonal Antibody (HC631014)

Name: Anti-Human FOXC1 Polyclonal Antibody
Brand: abinScience
SKU: HC631014
Price: 96 USD
Availability: InStock

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Overview

Catalog No.

HC631014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FOXC1 (Ser82-Glu163).

Target

FKHL7, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FREAC3, FREAC-3, FOXC1

Purification

Purified by antigen affinity column.

Accession

Q12948

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Forkhead box protein C1 (FOXC1) is a ~56 kDa protein. DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Acts as a transcriptional coactivator.

1. Berry, FB. et al. (2002) The Journal of biological chemistry 277, 10292-7. PMID: 11782474

2. Saleem, RA. et al. (2003) Human molecular genetics 12, 2993-3005. PMID: 14506133

3. Saleem, RA. et al. (2003) Investigative ophthalmology & visual science 44, 4608-12. PMID: 14578375

4. Murphy, TC. et al. (2004) Investigative ophthalmology & visual science 45, 2531-8. PMID: 15277473

5. Saleem, RA. et al. (2004) Nucleic acids research 32, 4182-93. PMID: 15299087

6. Berry, FB. et al. (2005) Molecular and cellular biology 25, 1415-24. PMID: 15684392

7. Berry, FB. et al. (2006) Human molecular genetics 15, 905-19. PMID: 16449236

8. Berry, FB. et al. (2006) The Journal of biological chemistry 281, 10098-104. PMID: 16492674

9. Ito, YA. et al. (2007) Archives of ophthalmology (Chicago, Ill. : 1960) 125, 128-35. PMID: 17210863

10. Ito, YA. et al. (2009) Investigative ophthalmology & visual science 50, 3573-9. PMID: 19279310

Note

For research use only.

Images

References

Datasheet

Anti-Human FOXC1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Anti-Human FOXC1 Polyclonal Antibody (HC631014)

Overview

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Datasheet

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