Human FOXC1 Recombinant Protein (N-GST & C-His) (HC631022)

Name: Human FOXC1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC631022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC631022
Description	Recombinant Human FOXC1 Protein, N-GST & C-His (HC631022) expressed in E. coli, spanning Tyr81-Glu193. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q12948
Protein length	Tyr81-Glu193
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	41.81 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	FKHL7, FOXC1, FREAC-3, FREAC3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3
Background	Forkhead box protein C1 is a ~56 kDa protein. DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Acts as a transcriptional coactivator. 1. Berry, FB. et al. (2002) The Journal of biological chemistry 277, 10292-7. PMID: 11782474 2. Saleem, RA. et al. (2003) Human molecular genetics 12, 2993-3005. PMID: 14506133 3. Saleem, RA. et al. (2003) Investigative ophthalmology & visual science 44, 4608-12. PMID: 14578375 4. Murphy, TC. et al. (2004) Investigative ophthalmology & visual science 45, 2531-8. PMID: 15277473 5. Saleem, RA. et al. (2004) Nucleic acids research 32, 4182-93. PMID: 15299087 6. Berry, FB. et al. (2005) Molecular and cellular biology 25, 1415-24. PMID: 15684392 7. Berry, FB. et al. (2006) Human molecular genetics 15, 905-19. PMID: 16449236 8. Berry, FB. et al. (2006) The Journal of biological chemistry 281, 10098-104. PMID: 16492674 9. Ito, YA. et al. (2007) Archives of ophthalmology (Chicago, Ill. : 1960) 125, 128-35. PMID: 17210863 10. Ito, YA. et al. (2009) Investigative ophthalmology & visual science 50, 3573-9. PMID: 19279310
Note	For research use only

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Datasheet

Human FOXC1 Recombinant Protein (N-GST & C-His).pdf

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Human FOXC1 Recombinant Protein (N-GST & C-His) (HC631022)

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