

| Numéro de catalogue | HD643012 |
|---|---|
| Description |
Recombinant Human GFM2 Protein, N-His (HD643012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q969S9 |
| Longueur de protéine | Ala461-Thr779 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | EC:3.6.5.-, EF-G2mt, EFG2, Elongation factor G 2, mitochondrial, Elongation factor G2, GFM2, RRF2mt, Ribosome-releasing factor 2, mitochondrial, hEFG2, mEF-G 2 |
| Contexte | Ribosome-releasing factor 2, mitochondrial is a ~86 kDa protein. Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. 1. Tsuboi, M. et al. (2009) Molecular cell 35, 502-10. PMID: 19716793 2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294 |
| Note | For research use only |
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