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| カタログ番号 | HD433012 |
|---|---|
| 説明 |
Recombinant Human GNL2 Protein, N-His (HD433012) expressed in E. coli, spanning Glu195-Arg455. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q13823 |
| タンパク質長 | Glu195-Arg455 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 32.02 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Autoantigen NGP-1, GNL2, NGP1, Nucleolar GTP-binding protein 2 |
| 背景 | Nucleolar GTP-binding protein 2 is a ~83 kDa protein. GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels. 1. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547 2. Datta, D. et al. (2015) The Journal of biological chemistry 290, 21536-52. PMID: 26203195 |
| 注意事項 | For research use only |
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