Anti-GNL2 Polyclonal Antibody (HD433014)

Name: Anti-GNL2 Polyclonal Antibody
Brand: abinScience
SKU: HD433014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HD433014

Description

Anti-GNL2 Polyclonal Antibody (HD433014) is a rabbit polyclonal antibody detecting GNL2 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GNL2 (Glu195-Arg455).

Target

Autoantigen NGP-1, GNL2, NGP1, Nucleolar GTP-binding protein 2

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q13823

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Q13823

Background

Nucleolar GTP-binding protein 2 (GNL2) is a ~83 kDa protein. GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.

1. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547

2. Datta, D. et al. (2015) The Journal of biological chemistry 290, 21536-52. PMID: 26203195

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-GNL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate

References

Datasheet

Anti-GNL2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-GNL2 Polyclonal Antibody (HD433014)

Overview

Images

References

Datasheet

SDS

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