Human GPR15LG Recombinant Protein (N-GST & C-His) (HD559012)

Name: Human GPR15LG Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HD559012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HD559012
Описание	Recombinant Human GPR15LG Protein, N-GST & C-His (HD559012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q6UWK7
Длина белка	Lys25-Val82
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	AP-57, Antimicrobial peptide with 57 amino acid residues, Antimicrobial peptide-57, C10orf99, CSBF, Colon-derived SUSD2 binding factor, GPR15L, GPR15LG, Protein GPR15 ligand, Protein GPR15L, Protein GPR15LG, Secreted protein C10orf99
Фон	Protein GPR15LG is a ~9 kDa protein. Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation. 1. Suply, T. et al. (2017) Science signaling 10. PMID: 28900043 2. Ocón, B. et al. (2017) Frontiers in immunology 8, 1111. PMID: 28936214 3. Pan, W. et al. (2014) Scientific reports 4, 6812. PMID: 25351403 4. Chen, C. et al. (2018) Scientific reports 8, 8590. PMID: 29872130 5. Tseng, PY. et al. (2022) Science advances 8, eabm7342. PMID: 35704588
Примечание	For research use only

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Даташит

Human GPR15LG Recombinant Protein (N-GST & C-His).pdf

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Formula

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C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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