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Anti-Human GPR15LG Polyclonal Antibody (HD559014)

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Overview
Catalog No.HD559014
Description
Anti-Human GPR15LG Polyclonal Antibody (HD559014) is a rabbit polyclonal antibody detecting Protein GPR15LG. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human GPR15LG (Lys25-Val82).
Target AP-57, Antimicrobial peptide with 57 amino acid residues, Antimicrobial peptide-57, C10orf99, CSBF, Colon-derived SUSD2 binding factor, GPR15L, GPR15LG, Protein GPR15 ligand, Protein GPR15L, Protein GPR15LG, Secreted protein C10orf99
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6UWK7
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Protein GPR15LG is a ~9 kDa protein. Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation.

1. Suply, T. et al. (2017) Science signaling 10. PMID: 28900043
2. Ocón, B. et al. (2017) Frontiers in immunology 8, 1111. PMID: 28936214
3. Pan, W. et al. (2014) Scientific reports 4, 6812. PMID: 25351403
4. Chen, C. et al. (2018) Scientific reports 8, 8590. PMID: 29872130
5. Tseng, PY. et al. (2022) Science advances 8, eabm7342. PMID: 35704588
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human GPR15LG Polyclonal Antibody

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