Human GPR37L1 Recombinant Protein (N-His-KSI) (HD416012)

Name: Human GPR37L1 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD416012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD416012
Descripción	Recombinant Human GPR37L1 Protein, N-His-KSI (HD416012) expressed in E. coli, spanning Ala26-Met134. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	O60883
Longitud de proteína	Ala26-Met134
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	27.68 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ETBR-LP-2, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1, GPR37L1
Fondo	G-protein coupled receptor 37-like 1 is a ~52 kDa protein. G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. 1. Coleman, JL. et al. (2016) Science signaling 9, ra36. PMID: 27072655 2. Meyer, RC. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 9529-34. PMID: 23690594 3. Giddens, MM. et al. (2017) Neurobiology of disease 106, 181-190. PMID: 28688853
Nota	For research use only

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Datasheet

Human GPR37L1 Recombinant Protein (N-His-KSI).pdf

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