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Human HNRNPC Recombinant Protein (N-GST & C-His) (HY366022)

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概要
カタログ番号HY366022
説明
Recombinant Human HNRNPC Protein, N-GST & C-His (HY366022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムE. coli
アクセッション番号P07910
タンパク質長Ser16-Ala85
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名HNRNPC, HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2
背景

Heterogeneous nuclear ribonucleoproteins C1/C2 is a ~33 kDa protein. Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing.

1. Huang, M. et al. (1994) Molecular and cellular biology 14, 518-33. PMID: 8264621
2. Kim, JH. et al. (2003) Molecular and cellular biology 23, 708-20. PMID: 12509468
3. Shetty, S. (2005) Molecular and cellular biochemistry 272, 107-18. PMID: 16010978
4. Sébillon, P. et al. (1995) Nucleic acids research 23, 3419-25. PMID: 7567451
5. Liu, N. et al. (2015) Nature 518, 560-4. PMID: 25719671
注意事項 For research use only
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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