

| カタログ番号 | HY366022 |
|---|---|
| 説明 |
Recombinant Human HNRNPC Protein, N-GST & C-His (HY366022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P07910 |
| タンパク質長 | Ser16-Ala85 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | HNRNPC, HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2 |
| 背景 | Heterogeneous nuclear ribonucleoproteins C1/C2 is a ~33 kDa protein. Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. 1. Huang, M. et al. (1994) Molecular and cellular biology 14, 518-33. PMID: 8264621 2. Kim, JH. et al. (2003) Molecular and cellular biology 23, 708-20. PMID: 12509468 3. Shetty, S. (2005) Molecular and cellular biochemistry 272, 107-18. PMID: 16010978 4. Sébillon, P. et al. (1995) Nucleic acids research 23, 3419-25. PMID: 7567451 5. Liu, N. et al. (2015) Nature 518, 560-4. PMID: 25719671 |
| 注意事項 | For research use only |
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