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Human HPN/Hepsin Recombinant Protein (N-His) (HY080012)

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Vista general
Número de catálogoHY080012
Descripción
Recombinant Human HPN/Hepsin Protein, N-His (HY080012) expressed in E. coli, spanning Gln55-Leu417. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP05981
Longitud de proteínaGln55-Leu417
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 41.71 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosEC:3.4.21.106, HPN, Serine protease hepsin, Serine protease hepsin catalytic chain, Serine protease hepsin non-catalytic chain, TMPRSS1, Transmembrane protease serine 1
Fondo

Serine protease hepsin is a ~45 kDa protein. Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.

1. Herter, S. et al. (2005) The Biochemical journal 390, 125-36. PMID: 15839837
2. Ganesan, R. et al. (2011) Molecular cancer research : MCR 9, 1175-86. PMID: 21875933
3. Torres-Rosado, A. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7181-5. PMID: 8346233
4. Heurich, A. et al. (2014) Journal of virology 88, 1293-307. PMID: 24227843
5. Brunati, M. et al. (2015) eLife 4, e08887. PMID: 26673890
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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