

| Catalog No. | HY080013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1938 | ||||
| Clonality | Monoclonal | ||||
| Target | TMPRSS1, Transmembrane protease serine 1, Serine protease hepsin, HPN | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P05981 | ||||
| RRID | Anti-Human HPN/Hepsin Antibody (SAA1938) (abinScience Cat# HY080013, RRID:AB_3727702) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Serine protease hepsin (HPN) is a ~45 kDa protein. Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. 1. Herter, S. et al. (2005) The Biochemical journal 390, 125-36. PMID: 15839837 2. Ganesan, R. et al. (2011) Molecular cancer research : MCR 9, 1175-86. PMID: 21875933 3. Torres-Rosado, A. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7181-5. PMID: 8346233 4. Heurich, A. et al. (2014) Journal of virology 88, 1293-307. PMID: 24227843 5. Brunati, M. et al. (2015) eLife 4, e08887. PMID: 26673890 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human HPN/Hepsin Antibody (SAA1938)
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