Human HPN/Hepsin Recombinant Protein (N-His) (HY080012)

Name: Human HPN/Hepsin Recombinant Protein (N-His)
Brand: abinScience
SKU: HY080012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HY080012
Description	Recombinant Human HPN/Hepsin Protein, N-His (HY080012) expressed in E. coli, spanning Gln55-Leu417. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P05981
Protein length	Gln55-Leu417
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	41.71 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.4.21.106, HPN, Serine protease hepsin, Serine protease hepsin catalytic chain, Serine protease hepsin non-catalytic chain, TMPRSS1, Transmembrane protease serine 1
Background	Serine protease hepsin is a ~45 kDa protein. Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. 1. Herter, S. et al. (2005) The Biochemical journal 390, 125-36. PMID: 15839837 2. Ganesan, R. et al. (2011) Molecular cancer research : MCR 9, 1175-86. PMID: 21875933 3. Torres-Rosado, A. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7181-5. PMID: 8346233 4. Heurich, A. et al. (2014) Journal of virology 88, 1293-307. PMID: 24227843 5. Brunati, M. et al. (2015) eLife 4, e08887. PMID: 26673890
Note	For research use only

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Datasheet

Human HPN/Hepsin Recombinant Protein (N-His).pdf

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Human HPN/Hepsin Recombinant Protein (N-His) (HY080012)

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