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| カタログ番号 | HY080012 |
|---|---|
| 説明 |
Recombinant Human HPN/Hepsin Protein, N-His (HY080012) expressed in E. coli, spanning Gln55-Leu417. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P05981 |
| タンパク質長 | Gln55-Leu417 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 41.71 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | EC:3.4.21.106, HPN, Serine protease hepsin, Serine protease hepsin catalytic chain, Serine protease hepsin non-catalytic chain, TMPRSS1, Transmembrane protease serine 1 |
| 背景 | Serine protease hepsin is a ~45 kDa protein. Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. 1. Herter, S. et al. (2005) The Biochemical journal 390, 125-36. PMID: 15839837 2. Ganesan, R. et al. (2011) Molecular cancer research : MCR 9, 1175-86. PMID: 21875933 3. Torres-Rosado, A. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7181-5. PMID: 8346233 4. Heurich, A. et al. (2014) Journal of virology 88, 1293-307. PMID: 24227843 5. Brunati, M. et al. (2015) eLife 4, e08887. PMID: 26673890 |
| 注意事項 | For research use only |
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