

| Numéro de catalogue | HV080021 |
|---|---|
| Description |
Recombinant Human IgG Protein (HV080021) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE.
Highlights
|
| Longueur de protéine | Full length. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | Ig gamma-1 chain C region EU, Immunoglobulin heavy constant gamma 1, IGHG1, Ig gamma-1 chain C region NIE, Ig gamma-1 chain C region, Ig gamma-1 chain C region KOL |
| Contexte | Immunoglobulin heavy constant gamma 1 (IgG) is a ~43 kDa protein. Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding to a specific antigen trigger the clonal expansion and differentiation of B lymphocytes into Ig-secreting plasma cells. Secreted Igs known as antibodies mediate the effector phase of humoral immunity by blocking the interaction of infectious antigens with cellular receptors (via the antigen-binding region) and eliciting effector mechanisms that lead to pathogen neutralization (via the constant region). The antigen-binding region is formed by the variable domain of one heavy chain paired with the variable domain of its associated light chain. 1. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 2. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 3. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 |
| Note | For research use only. |

SDS-PAGE for Recombinant Human IgG Protein




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