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Human IL-6 Recombinant Protein (C-Strep) (HY328051)

Human IL-6 Recombinant Protein (C-Strep)
Human IL-6 Recombinant Protein (C-Strep)
Human IL-6 Recombinant Protein (C-Strep)
Human IL-6 Recombinant Protein (C-Strep)
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  • 概要

  • イメージ

  • 参考文献

  • データシート

  • SDS

概要
カタログ番号HY328051
説明
Recombinant Human IL6 Protein, C-Strep (HY328051) expressed in Mammalian Cells, spanning Met1-Met212. Purity: >90% by SDS-PAGE.
Highlights
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号P05231
タンパク質長Met1-Met212
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
ターゲット B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 24.89 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6
背景

Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

注意事項 For research use only
イメージ
  • Human IL-6 Recombinant Protein (C-Strep)

    Bioactivity

    Immobilized HY328051 Human IL6 Recombinant Protein (C-Strep) at 2 μg/mL(100 μL/well) can bind HY583011 Human CD126/IL6R/IL-6RA Recombinant Protein (C-His), the EC 50 is 1.55 μg/mL.

  • Human IL-6 Recombinant Protein (C-Strep)

    Bioactivity

    Immobilized HY328051 Human IL6 Recombinant Protein (C-Strep) at 2 μg/mL(100 μL/well) can bind HY583021 Human CD126/IL6R/IL-6RA Recombinant Protein (C-Fc), the EC 50 is 267 ng/mL.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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