Human IL-6 Recombinant Protein (N-HSAD3 & C-His) (HY328041)

Name: Human IL-6 Recombinant Protein (N-HSAD3 & C-His)
Brand: abinScience
SKU: HY328041
Price: 298 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue	HY328041
Description	Recombinant Human IL6 Protein, N-HSAD3 & C-His (HY328041) expressed in Mammalian Cells, spanning Ala28-Met212. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	Mammalian cells
Numéro d'accès	P05231
Longueur de protéine	Ala28-Met212
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Cible	B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	47.73 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6
Contexte	Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For research use only

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Bioactivity

Immobilized HY328041 Human IL6 Recombinant Protein (N-HSAD3 & C-His) at 2 μg/mL(100 μL/well) can bind HY583021 Human CD126/IL6R/IL-6RA Recombinant Protein (C-Fc), the EC 50 is 133 ng/mL.
Bioactivity

Immobilized CY583021 Canine CD126/IL6R/IL-6RA Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HY328041 Human IL6 Recombinant Protein (N-HSAD3 & C-His), the EC 50 is 983 ng/mL.