Human KLHL24 Recombinant Protein (N-His) (HD515012)

Name: Human KLHL24 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD515012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD515012
Descripción	Recombinant Human KLHL24 Protein, N-His (HD515012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q6TFL4
Longitud de proteína	Arg306-Leu600
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	DRE1, KLHL24, KRIP6, Kainate receptor-interacting protein for GluR6, Kelch-like protein 24, Protein DRE1
Fondo	Kelch-like protein 24 is a ~68 kDa protein. Necessary to maintain the balance between intermediate filament stability and degradation, a process that is essential for skin integrity. As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14 and controls its levels during keratinocytes differentiation. Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties. Has a crucial role in cardiac development and function. 1. He, Y. et al. (2016) American journal of human genetics 99, 1395-1404. PMID: 27889062 2. Lin, Z. et al. (2016) Nature genetics 48, 1508-1516. PMID: 27798626 3. Hedberg-Oldfors, C. et al. (2019) Human molecular genetics 28, 1919-1929. PMID: 30715372
Nota	For research use only

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Referencias

Datasheet

Human KLHL24 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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