Human KMT5A Recombinant Protein (N-His) (HP554022)

Name: Human KMT5A Recombinant Protein (N-His)
Brand: abinScience
SKU: HP554022
Price: 211 USD
Availability: InStock

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概要

カタログ番号	HP554022
説明	Recombinant Human KMT5A Protein, N-His (HP554022) expressed in E. coli, spanning Ser231-His393. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	E. coli
アクセッション番号	Q9NQR1
タンパク質長	Ser231-His393
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	20.82 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	EC:2.1.1.-, EC:2.1.1.361, H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, KMT5A, Lysine N-methyltransferase 5A, Lysine-specific methylase 5A, N-lysine methyltransferase KMT5A, PR-Set7, PR/SET domain-containing protein 07, PR/SET07, PRSET7, SET domain-containing protein 8, SET07, SET8, SETD8
背景	N-lysine methyltransferase KMT5A is a ~42 kDa protein. Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. 1. Nishioka, K. et al. (2002) Molecular cell 9, 1201-13. PMID: 12086618 2. Fang, J. et al. (2002) Current biology : CB 12, 1086-99. PMID: 12121615 3. Yin, Y. et al. (2005) The Journal of biological chemistry 280, 30025-31. PMID: 15964846 4. Shi, X. et al. (2007) Molecular cell 27, 636-46. PMID: 17707234 5. Saredi, G. et al. (2016) Nature 534, 714-718. PMID: 27338793 6. Julien, E. et al. (2004) Molecular cell 14, 713-25. PMID: 15200950 7. Xiao, B. et al. (2005) Genes & development 19, 1444-54. PMID: 15933069 8. Couture, JF. et al. (2005) Genes & development 19, 1455-65. PMID: 15933070
注意事項	For research use only

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データシート

Human KMT5A Recombinant Protein (N-His).pdf

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Human KMT5A Recombinant Protein (N-His) (HP554022)

概要

イメージ

参考文献

データシート

SDS

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