Human LRRC8E Recombinant Protein (N-His) (HD329012)

Name: Human LRRC8E Recombinant Protein (N-His)
Brand: abinScience
SKU: HD329012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HD329012
Описание	Recombinant Human LRRC8E Protein, N-His (HD329012) expressed in E. coli, spanning Leu411-Glu796. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q6NSJ5
Длина белка	Leu411-Glu796
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	45.56 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	LRRC8E, Leucine-rich repeat-containing protein 8E, Volume-regulated anion channel subunit LRRC8E
Фон	Volume-regulated anion channel subunit LRRC8E is a ~90 kDa protein. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Mediates efflux of amino acids, such as aspartate, in response to osmotic stress. The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition. 1. Voss, FK. et al. (2014) Science (New York, N.Y.) 344, 634-8. PMID: 24790029 2. Syeda, R. et al. (2016) Cell 164, 499-511. PMID: 26824658 3. Lutter, D. et al. (2017) Journal of cell science 130, 1122-1133. PMID: 28193731 4. Lahey, LJ. et al. (2020) Molecular cell 80, 578-591.e5. PMID: 33171122
Примечание	For research use only

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Human LRRC8E Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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