

| Каталожный номер | HP852012 |
|---|---|
| Описание |
Recombinant Human MOSPD2 Protein, N-His (HP852012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q8NHP6 |
| Длина белка | Ala2-Ser261&Gly325-Gln496 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 52.28 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | MOSPD2, Motile sperm domain-containing protein 2 |
| Фон | Motile sperm domain-containing protein 2 is a ~59 kDa protein. Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines. 1. Di Mattia, T. et al. (2018) EMBO reports 19. PMID: 29858488 2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732 3. Zouiouich, M. et al. (2022) The Journal of cell biology 221. PMID: 35389430 4. Mendel, I. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2125-2132. PMID: 28137892 |
| Примечание | For research use only |



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