

| Número de catálogo | HA929022 |
|---|---|
| Descripción |
Recombinant Human NOCT Protein, N-His (HA929022) expressed in E. coli, spanning Thr120-Ser431. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q9UK39 |
| Longitud de proteína | Thr120-Ser431 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 37.85 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin |
| Fondo | Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. 1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539 2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338 |
| Nota | For research use only |
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