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Anti-Human NOCT Polyclonal Antibody (HA929014)

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Overview
Catalog No.HA929014
Description
Anti-Human NOCT Polyclonal Antibody (HA929014) is a rabbit polyclonal antibody detecting NOCT. Suitable for Mouse, Rat, and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human NOCT (Thr120-Ser431).
Target CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9UK39
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis.

1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539
2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human NOCT Polyclonal Antibody

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