

| カタログ番号 | HP612022 |
|---|---|
| 説明 |
Recombinant Human PACSIN2 Protein, N-His (HP612022) expressed in E. coli, spanning Val21-Gly293. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9UNF0 |
| タンパク質長 | Val21-Gly293 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 34.41 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | PACSIN2, Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II |
| 背景 | Protein kinase C and casein kinase substrate in neurons protein 2 is a ~55 kDa protein. Regulates the morphogenesis and endocytosis of caveolae. Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Essential for endothelial organization in sprouting angiogenesis, modulates CDH5-based junctions. 1. de Kreuk, BJ. et al. (2011) Journal of cell science 124, 2375-88. PMID: 21693584 2. de Kreuk, BJ. et al. (2012) The Journal of biological chemistry 287, 43438-53. PMID: 23129763 3. Goh, SL. et al. (2012) PloS one 7, e51628. PMID: 23236520 4. Giridharan, SS. et al. (2013) Molecular biology of the cell 24, 1776-90, S1-15. PMID: 23596323 |
| 注意事項 | For research use only |
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