Anti-Human PACSIN2 Polyclonal Antibody (HP612014)

Name: Anti-Human PACSIN2 Polyclonal Antibody
Brand: abinScience
SKU: HP612014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP612014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PACSIN2 (Ser425-Gln486).

Target

Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II, PACSIN2

Purification

Purified by antigen affinity column.

Accession

Q9UNF0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) is a ~55 kDa protein. Regulates the morphogenesis and endocytosis of caveolae. Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Essential for endothelial organization in sprouting angiogenesis, modulates CDH5-based junctions.

1. de Kreuk, BJ. et al. (2011) Journal of cell science 124, 2375-88. PMID: 21693584

2. de Kreuk, BJ. et al. (2012) The Journal of biological chemistry 287, 43438-53. PMID: 23129763

3. Goh, SL. et al. (2012) PloS one 7, e51628. PMID: 23236520

4. Giridharan, SS. et al. (2013) Molecular biology of the cell 24, 1776-90, S1-15. PMID: 23596323

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human PACSIN2 polyclonal antibody at 1ug/mL on recombinant Human PACSIN2 (Catalog No. HP612012).

References

Datasheet

Anti-Human PACSIN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PACSIN2 Polyclonal Antibody (HP612014)

Overview

Images

References

Datasheet

SDS

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