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Human PRAP1 Recombinant Protein (N-GST & C-His) (HA024032)

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概要
カタログ番号HA024032
説明
Recombinant Human PRAP1/uPA Protein, N-GST & C-His (HA024032) expressed in E. coli, spanning Val21-Gln151. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムE. coli
アクセッション番号Q96NZ9
タンパク質長Val21-Gln151
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 43.17 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Epididymis tissue protein Li 178, PRAP1, Proline-rich acidic protein 1, UPA, Uterine-specific proline-rich acidic protein
背景

Proline-rich acidic protein 1 is a ~17 kDa protein. Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas.

1. Zhang, J. et al. (2003) Cancer research 63, 6658-65. PMID: 14583459
2. Huang, BH. et al. (2012) Cell death & disease 3, e442. PMID: 23235459
3. Sze, KM. et al. (2014) The Journal of pathology 233, 51-60. PMID: 24374861
注意事項 For research use only
イメージ
参考文献
Formula
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