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Обзор
Каталожный номерHP302022
Описание
Recombinant Human RBM24 Protein, N-GST & C-His (HP302022) expressed in E. coli, spanning Thr11-Lys91. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессииE. coli
Номер доступаQ9BX46
Длина белкаThr11-Lys91
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыHomo sapiens (Human)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса 37.06 kDa
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияRBM24, RNA-binding motif protein 24, RNA-binding protein 24, RNA-binding region-containing protein 6, RNPC6
Фон

RNA-binding protein 24 is a ~24 kDa protein. Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes.

1. Jin, D. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 1158-67. PMID: 20977548
2. Xu, E. et al. (2014) Molecular cancer research : MCR 12, 359-69. PMID: 24375645
3. Lin, Y. et al. (2018) The international journal of biochemistry & cell biology 94, 10-21. PMID: 29104163
4. Zhang, M. et al. (2018) Cell death and differentiation 25, 1118-1130. PMID: 29358667
5. Zhang, T. et al. (2016) Stem cells (Dayton, Ohio) 34, 1776-89. PMID: 26990106
6. Jiang, Y. et al. (2014) The Journal of biological chemistry 289, 3164-75. PMID: 24356969
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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