

| Каталожный номер | HV262011 |
|---|---|
| Описание |
Recombinant Human RNASE7 Protein, C-His (HV262011) expressed in Yeast Cells, spanning Lys29-Leu156. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | Yeast cells |
| Номер доступа | Q9H1E1 |
| Длина белка | Lys29-Leu156 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 15.82 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | EC:3.1.27.-, RNASE7, RNase 7, Ribonuclease 7, SAP-2, Skin-derived antimicrobial protein 2 |
| Фон | Ribonuclease 7 is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. 1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054 2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768 3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966 4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772 5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125 |
| Примечание | For research use only |
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