Anti-RNASE7 Polyclonal Antibody (HV262014)

Name: Anti-RNASE7 Polyclonal Antibody
Brand: abinScience
SKU: HV262014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV262014

Description

Anti-RNASE7 Polyclonal Antibody (HV262014) is a rabbit polyclonal antibody detecting RNASE7 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RNASE7 (Lys31-Val155).

Target

Skin-derived antimicrobial protein 2, RNASE7, Ribonuclease 7, RNase 7, SAP-2

Purification

Purified by antigen affinity column.

Accession

Q9H1E1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ribonuclease 7 (RNASE7) is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.

1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054

2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768

3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966

4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772

5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125

Note

For research use only.

Images

References

Datasheet

Anti-RNASE7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-RNASE7 Polyclonal Antibody (HV262014)

Overview

Images

References

Datasheet

SDS

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