Human ROBO1 Recombinant Protein (N-His) (HP485022)

Name: Human ROBO1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP485022
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HP485022
説明	Recombinant Human ROBO1 Protein, N-His (HP485022) expressed in E. coli, spanning Arg69-Glu260. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	E. coli
アクセッション番号	Q9Y6N7
タンパク質長	Arg69-Glu260
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	23.65 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	DUTT1, Deleted in U twenty twenty, H-Robo-1, ROBO1, Roundabout homolog 1
背景	Roundabout homolog 1 is a ~180 kDa protein. Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA. May be required for lung development. 1. Brose, K. et al. (1999) Cell 96, 795-806. PMID: 10102268 2. Leyva-Díaz, E. et al. (2014) Current biology : CB 24, 494-508. PMID: 24560577 3. Kong, R. et al. (2015) The Journal of clinical investigation 125, 4407-20. PMID: 26529257
注意事項	For research use only