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| カタログ番号 | HD071012 |
|---|---|
| 説明 |
Recombinant Human SEC24C Protein, N-His (HD071012) expressed in E. coli, spanning Asp324-Ser1094. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P53992 |
| タンパク質長 | Asp324-Ser1094 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 88.31 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C |
| 背景 | Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5. 1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955 2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046 3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296 4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317 |
| 注意事項 | For research use only |
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