Anti-Human SEC24C Polyclonal Antibody (HD071014)

Name: Anti-Human SEC24C Polyclonal Antibody
Brand: abinScience
SKU: HD071014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HD071014

Description

Anti-Human SEC24C Polyclonal Antibody (HD071014) is a rabbit polyclonal antibody detecting SEC24C. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SEC24C (Asp324-Ser1094).

Target

KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P53992

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5.

1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955

2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046

3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296

4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317

Note

For research use only

Images

References

Datasheet

Anti-Human SEC24C Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SEC24C Polyclonal Antibody (HD071014)

Overview

Images

References

Datasheet

SDS

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