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| カタログ番号 | HW839022 |
|---|---|
| 説明 |
Recombinant Human SLC16A2 Protein, N-GST & C-His (HW839022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P36021 |
| タンパク質長 | Tyr280-Arg322 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | MCT 7, MCT 8, MCT7, MCT8, Monocarboxylate transporter 7, Monocarboxylate transporter 8, SLC16A2, Solute carrier family 16 member 2, X-linked PEST-containing transporter, XPCT |
| 背景 | Monocarboxylate transporter 8 is a ~59 kDa protein. Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). 1. Friesema, EC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2761-72. PMID: 16887882 2. Friesema, EC. et al. (2008) Molecular endocrinology (Baltimore, Md.) 22, 1357-69. PMID: 18337592 3. Kinne, A. et al. (2010) The Journal of biological chemistry 285, 28054-63. PMID: 20628049 4. Kersseboom, S. et al. (2013) Molecular endocrinology (Baltimore, Md.) 27, 801-13. PMID: 23550058 5. Armour, CM. et al. (2015) PloS one 10, e0139343. PMID: 26426690 6. Novara, F. et al. (2017) Human mutation 38, 260-264. PMID: 27805744 7. Groeneweg, S. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1499-1510. PMID: 31436139 8. Vatine, GD. et al. (2017) Cell stem cell 20, 831-843.e5. PMID: 28526555 |
| 注意事項 | For research use only |
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