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| カタログ番号 | HC768012 |
|---|---|
| 説明 |
Recombinant Human SLC29A2 Protein, N-GST & C-His (HC768012) expressed in E. coli, spanning Lys217-Lys289. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q14542 |
| タンパク質長 | Lys217-Lys289 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 36.35 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 36 kDa nucleolar protein HNP36, DER12, Delayed-early response protein 12, ENT2, Equilibrative NBMPR-insensitive nucleoside transporter, Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, Equilibrative nucleoside transporter 2, HNP36, Hydrophobic nucleolar protein, 36 kDa, Nucleoside transporter, ei-type, SLC29A2, Solute carrier family 29 member 2, hENT2 |
| 背景 | Equilibrative nucleoside transporter 2 is a ~50 kDa protein. Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 3. Ward, JL. et al. (2003) Archives of biochemistry and biophysics 411, 19-26. PMID: 12590919 4. Owen, RP. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 12-5. PMID: 16214850 5. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 6. Griffiths, M. et al. (1997) The Biochemical journal 328 ( Pt 3), 739-43. PMID: 9396714 7. Crawford, CR. et al. (1998) The Journal of biological chemistry 273, 5288-93. PMID: 9478986 |
| 注意事項 | For research use only |
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