InVivoMAb Anti-Human ENT2 Antibody (Iv0157) (HY377010)

Name: InVivoMAb Anti-Human ENT2 Antibody (Iv0157)
Brand: abinScience
SKU: HY377010
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HY377010
Description	InVivoMAb Anti-Human ENT2/SLC29A2 Antibody (Iv0157) [Iv0157] (HY377010) is a human monoclonal antibody detecting Equilibrative nitrobenzylmercaptopurine riboside-insensit... in ELISA, Neutralization. Suitable for Human.
Species reactivity	Human
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	Iv0157
Clonality	Monoclonal
Target	Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, 36 kDa nucleolar protein HNP36, ENT2, Equilibrative nucleoside transporter 2, SLC29A2, Hydrophobic nucleolar protein, 36 kDa, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, Delayed-early response protein 12, Solute carrier family 29 member 2, HNP36, DER12
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q14542
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Equilibrative nucleoside transporter 2 (ENT2/SLC29A2) is a ~50 kDa protein. Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 3. Ward, JL. et al. (2003) Archives of biochemistry and biophysics 411, 19-26. PMID: 12590919 4. Owen, RP. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 12-5. PMID: 16214850 5. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 6. Griffiths, M. et al. (1997) The Biochemical journal 328 ( Pt 3), 739-43. PMID: 9396714 7. Crawford, CR. et al. (1998) The Journal of biological chemistry 273, 5288-93. PMID: 9478986
Note	For research use only. Not suitable for clinical or therapeutic use.

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InVivoMAb Anti-Human ENT2 Antibody (Iv0157).pdf

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InVivoMAb Anti-Human ENT2 Antibody (Iv0157) (HY377010)

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