Human SLC39A7 Recombinant Protein (N-His) (HD636012)

Name: Human SLC39A7 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD636012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HD636012
Description	Recombinant Human SLC39A7 Protein, N-His (HD636012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q92504
Longueur de protéine	Gly30-Thr133
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	HKE4, Histidine-rich membrane protein Ke4, RING5, Really interesting new gene 5 protein, SLC39A7, Solute carrier family 39 member 7, ZIP7, Zinc transporter SLC39A7, Zrt-, Irt-like protein 7
Contexte	Zinc transporter SLC39A7 is a ~50 kDa protein. Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling. Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle. 1. Taylor, KM. et al. (2004) The Biochemical journal 377, 131-9. PMID: 14525538 2. Huang, L. et al. (2005) The Journal of biological chemistry 280, 15456-63. PMID: 15705588 3. Nimmanon, T. et al. (2017) Metallomics : integrated biometal science 9, 471-481. PMID: 28205653 4. Woodruff, G. et al. (2018) Molecular pharmacology 94, 1092-1100. PMID: 29980658 5. Taylor, KM. et al. (2012) Science signaling 5, ra11. PMID: 22317921 6. Anzilotti, C. et al. (2019) Nature immunology 20, 350-361. PMID: 30718914 7. Fauster, A. et al. (2019) Cell death and differentiation 26, 1138-1155. PMID: 30237509
Note	For research use only

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Human SLC39A7 Recombinant Protein (N-His).pdf

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