Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

Name: Anti-Human SLC39A7 Polyclonal Antibody
Brand: abinScience
SKU: HD636014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HD636014

Description

Anti-Human SLC39A7 Polyclonal Antibody (HD636014) is a rabbit polyclonal antibody detecting SLC39A7. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC39A7 (Gly30-Thr133).

Target

HKE4, Histidine-rich membrane protein Ke4, RING5, Really interesting new gene 5 protein, SLC39A7, Solute carrier family 39 member 7, ZIP7, Zinc transporter SLC39A7, Zrt-, Irt-like protein 7

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q92504

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Zinc transporter SLC39A7 is a ~50 kDa protein. Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling. Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle.

1. Taylor, KM. et al. (2004) The Biochemical journal 377, 131-9. PMID: 14525538

2. Huang, L. et al. (2005) The Journal of biological chemistry 280, 15456-63. PMID: 15705588

3. Nimmanon, T. et al. (2017) Metallomics : integrated biometal science 9, 471-481. PMID: 28205653

4. Woodruff, G. et al. (2018) Molecular pharmacology 94, 1092-1100. PMID: 29980658

5. Taylor, KM. et al. (2012) Science signaling 5, ra11. PMID: 22317921

6. Anzilotti, C. et al. (2019) Nature immunology 20, 350-361. PMID: 30718914

7. Fauster, A. et al. (2019) Cell death and differentiation 26, 1138-1155. PMID: 30237509

Note

For research use only

Images

References

Datasheet

Anti-Human SLC39A7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

Overview

Images

References

Datasheet

SDS

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