Human SLC5A1 Recombinant Protein (N-His) (HB272012)

Name: Human SLC5A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB272012
Price: 211 USD
Availability: InStock

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Número de catálogo	HB272012
Descripción	Recombinant Human SLC5A1 Protein, N-His (HB272012) expressed in E. coli. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P13866
Longitud de proteína	Asp230-Pro277&Ser335-Gly380&Arg564-Thr643
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	22.70 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	High affinity sodium-glucose cotransporter, NAGT, Na(+)/glucose cotransporter 1, SGLT1, SLC5A1, Sodium/glucose cotransporter 1, Solute carrier family 5 member 1
Fondo	Sodium/glucose cotransporter 1 is a ~73 kDa protein. Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis. 1. Hummel, CS. et al. (2011) American journal of physiology. Cell physiology 300, C14-21. PMID: 20980548 2. Han, L. et al. (2022) Nature 601, 274-279. PMID: 34880492 3. Kamitori, K. et al. (2022) Journal of molecular biology 434, 167464. PMID: 35077764 4. Martín, MG. et al. (1996) Nature genetics 12, 216-20. PMID: 8563765 5. Cui, W. et al. (2023) Nature communications 14, 2920. PMID: 37217492 6. Salker, MS. et al. (2017) Scientific reports 7, 12612. PMID: 28974690
Nota	For research use only

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Referencias

Datasheet

Human SLC5A1 Recombinant Protein (N-His).pdf

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C₁ (Stock Conc.)

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